This particular screenshot is from Legend of Heroes: Trails in the Sky, but it occurs in every other game as well. Whenever I open a menu, the screen transitions or even when a text box comes up, the game fuzzes out like this.
The problem doesn't happen with Non-Buffered Rendering, but that comes with its own set of problems, like in-engine cutscenes just being completely black with the exception of text boxes, lots of graphical problems etc.
No one else has this problem with Legend of Heroes, so I assume it must be some kind of issue with my hardware, software or settings. I haven't played much with the settings though.
It's strange that on the same game and same version of the app I was able to play this game without the graphical glitch on the LG G4 but since I changed to a Samsung Galaxy Note 5 and subsequently to the Samsung Galaxy S6 Edge plus this happened. I've tried every setting.
This happens even when you reset to default settings?
It might be a driver bug on your device. Are there any updates available (I think they released an Android update recently, might be available for the Nexus 6.)