Debug Problem

[evilgoku]

Hello sir
I have a problem With Final Fantasy I II (E).iso
breakpoint is 0887f41c
I Change with nop
08 00 02 A5 into 00 00 00 00 work fine BUT
i search value "08 00 02 A5" in Final Fantasy I II (E).iso
08 00 02 A5 and replace with 00 00 00 00
when i play Final Fantasy I II (E).iso again but no affect

is there a problem in Final Fantasy I II (E).iso or My breakpoint is incorrect